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bioRxiv: Study Found the Global SARS-CoV-2 Is Composed of Six Main Subtypes

The World Health Organization announced the global pandemic of COVID-19 in March 2020, the second pandemic in the 21st century. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an RNA beta coronavirus of the Coronaviridae family. The expansion of virus populations, such as SARS-CoV-2, has accumulated many shared polymorphisms, which has caused confusion in traditional clustering methods. In this case, a method to reduce the complexity of the sequence space occupied by the SARS-CoV-2 population is necessary for accurate clustering.

Recently, researchers from the Federal University of Ubrantia, the Federal University of Visosa, and the University of Brasilia, Brazil, proposed to subdivide the global SARS-CoV-2 population into 16 well-defined subtypes by focusing on polymorphisms in widely shared nonstructural cistrons (nsp3, nsp4, nsp6, nsp12, nsp13, and nsp14), structural genes (spike proteins and nucleocapsid), and accessory genes (ORF8). The related research results were published on the preprint server bioRxiv, and the article title is “The global population of SARS-CoV-2 is composed of six major subtypes”.

The researchers found that the six virus subtypes dominate the patient population, but all 16 subtypes of viruses exhibit amino acid substitutions that may have phenotypic significance. The researchers speculate that the virus subtypes detected in this study are records of the early stages of SARS-CoV-2 diversification. These viruses are randomly sampled to form virus populations around the world, which is a typical founder effect.

The researchers said that the genetic structure of the virus identified by SARS-CoV-2 infected persons provides substantial guidance for maximizing the effectiveness of candidate vaccines or drug trials.

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Natural Sinus Infection Remedies For Immediate Relief From Blockage

Inflammation and congestion of the sinuses is known as sinus infection which is very dangerous if not taken care. Sinuses are a system of hollow cavities in the skull and around an inch across; the largest sinus cavities are located. The sinuses are lined typically with tissue called mucosa which is soft and pink. There are many causes that block this passage such as indoor and outdoor airborne allergens. There are also dietary irritants like dairy, gluten, and chemical additives. There are several supplements available for the problem that are antibiotics, steroids, anti-inflammatory medication and in some cases, surgery. There are natural remedies which can solve the problem in an effective and safe manner possible.

It is essential to stay hydrated. This is important as it will help to clear the infection. It is advised to drink plenty of water, no sugar added juices, clear broth and hot tea. These fluids will help to thin out mucus and help to drain it away from irritated sinuses as the natural sinus infection remedies for immediate relief from blockage. It should be followed regularly.

It is advised to avoid drinking alcohol, caffeine, and sugary beverages, as well as from smoking. All of these substances will worsen the situation as they will dehydrate the system and cause mucus to thicken and clog already inflamed airways. It is advised to drink warm water instead as the natural sinus infection remedies for immediate relief from blockage.

It is advised to have spicy food. This will help to dissolve excess mucus. This includes foods like cayenne pepper or horseradish that can be mixed with apple cider vinegar and lemon juice as the best sinus infection remedies for immediate relief from blockage and pain.

It is advised to breathe well by following acupressure point activation. It will help to open the closed nasal passages. It is important to perform yoga and easy breathing exercises as the popular sinus infection remedies for relief and irritation. It removes the blockage too.

It is advised to follow simple procedure like steam inhalation. It helps to dissolve the mucus. This steam inhalation can be prepared by mixing few drops of eucalyptus or peppermint oil in hot water. A towel should be draped over the back of head and steam should be inhaled as the effective sinus infection remedies for relief from blockage and sinus.

The use of vitamin C is suggested as it will help the body to resist immune system deficiencies and improve overall health. It is the natural sinus infection remedies for strong relief from blockage and reduces pain to a great extent. It will help to feel calm and relaxed through regular use.

The use of fermented cod liver oil is recommended as it is rich in vitamins A and D, as well as omega-3 fatty acids. It is effective and suggested sinus infection remedies that can be taken after meals.

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5 Tips for Home Insurance Discounts

Once you are aware of this, it will certainly ease your premium payments to know when you are paying too much and areas where you can easily get big discounts. Here are some tips to get discounts on your home insurance.

1. Old to New: Insurers are always wary of the ‘old’. Older buildings, old wiring or non-weather proof roofing means that they may not be as effective at holding strong through extreme weather, storms, theft or other accidents. Hence, if you have your house renovated, or get new wiring done for the entire home, you should get a discount of up to ten percent. Stats from the Fire department show a high number of accidents due to old wiring, weak roofing, old fire-places etc.

2. Neighborhood safety: Insurance companies feel comfortable when they know you’re doing everything you can to keep your home safe. A safe home, keeps money in the insurer’s pocket. Thus, they like to encourage their policy holders by providing discounts whenever they take steps to reduce possible claims. Initiating or becoming a part of a home owner’s association can mean that as neighbor’s watch out for each other, the risk of loss through theft is greatly reduced. Additionally, having a home in a gated community also reduces risk. Hence great discounts can be obtained simply by informing your insurer about these facts.

3. Automatic Payments: As simple as it sounds, setting up recurring payment for your premium will also provide you a small discount, with the added benefit of not having to manually pay your insurer every time your premium is due.

4. Multi-policy discount: Many insurers provide discounts up to thirty percent, if you buy all your insurance (Automotive, home, business etc.,) from them. The discounts offered are a sort of reward for being loyal clients. The policies need not be of the same type, however, the insurance company does need to be the same. This discount may not always be possible if you’re buying your insurance from an insurance agent.

5. Discount on being claims-free: As mentioned earlier, insurance companies are delighted by anyone who reduces their risks and by those who have not claimed insurance anywhere from five years or more. Each insurer will have a different time period stated to avail this discount, so ask around, and you’re sure to get a discount of up to twenty percent, when you’re claims-free.
These are just five great ways to save on your premium payments, talk to your Insurer and you’re sure to get more discounts you never knew was possible.

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